Activated vitamin B2 and B6 provide additional cofactor support for optimum metabolism.Invaluable for delivering highly focused clinical methylation support, and the optimisation of cardiovascular, neurological and detoxification function.
Indications:
- A balanced and synergistic blend of methylation-supportive B vitamins
- Provides the externally methylated forms of folate and vitamin B12
- Activated forms of vitamin B2 and B6 provide crucial co-factor support for the proper metabolism of folate, B12 and methylation
- May provide a therapeutic dose of choline for support of the alternate BHMT homocysteine methylation pathway
- May help to support the maintenance of normal, healthy homocysteine levels via remethylation back to methionine
- Provides vitamin B6 for conversion of homocysteine to cysteine via the transulfation pathway
- May support the synthesis of glutathione
- Vitamin B2 is a component of glutathione reductase and a crucial cofactor in the activity of MTHFR
- Choline may support normal lipid metabolism
- Choline may assists in the synthesis of SAMe
- Choline serves as a valuable precursor for the synthesis of acetylcholine and phosphatidylcholine
Ingredients
Ingredient | Per 1 cap |
---|---|
Riboflavin sodium phosphate (Activated Vitamin B2)
equiv. Riboflavin (Vitamin B2)
|
31.7 mg
25 mg
|
Pyridoxal 5-phosphate (Activated Vitamin B6)
equiv. Pyridoxine (Vitamin B6)
|
29.2 mg
20 mg
|
Levomefolate calcium (Activated Vitamin B9)
equiv. Levomefolic acid (L-5-MTHF) (Activated Vitamin B9)
|
550 mcg
500 mcg
|
Mecobalamin (Co-methylcobalamin) (Activated Vitamin B12)
|
1000 mcg
|
Choline dihydrogen citrate
|
300 mg
|
Excipients: Leucine, Microcrystalline Cellulose, Tapioca Starch, Colloidal Anhydrous Silica
Use Suggestion
Adults take 1 capsule daily or as prescribed by your healthcare practitioner.
Store below 25° in a cool, dry, dark place.
Cautions
For Practitioner Dispensing Only
This product contains Pyridoxal-5-Phosphate which may be dangerous when used in large amounts or for a long time.
If symptoms persist consult your healthcare practitioner.
Vitamin supplements should not replace a balanced diet.
Known Side Effects
In doses typically administered for therapeutic purposes, 5-MTHF is considered non-toxic. At doses over 10mg daily, gastrointestinal complaints, insomnia, irritability, and fatigue have been reported.
Whilst some concern exists that supplementation with high doses of folic acid could mask a vitamin B12 deficiency, supplementation with 5-MTHF appears to sidestep this potential problem. Since 5-MTHF can only be converted to 5,10-methylenetetrahydrofolate (involved in DNA synthesis) after participating in homocysteine recycling with vitamin B12, 5-MTHF will not mask a B12 deficiency.
Medication Interactions
The activity of various B vitamins may affect, or be affected by, the presence of certain medications, including anticonvulsant and anti-inflammatory medications. Qualified consultation is advised when using these concomitantly.
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